Hyalie Esther Yamins Greene was born on March 19, 1919, in Fall River, Massachusetts. She was the eldest of two children born to Jacob Yamins and Frances Smolensky Yamins. Her father was born in Kalwaria in the Russian Empire and her mother was born in Fall River, Massachusetts, to parents also born in the Russian Empire. Sybil Eleanor Yamins Goldberg (1919-2018) was her only sibling; she also attended Black Mountain College (BMC) from 1938 to 1940.

Yamins learned about BMC from author Louis Adamic’s writings, where BMC was praised as an example of progressive education that would help bring about the inclusive and ethnically diverse America that Adamic championed. Having never visited North Carolina, Yamins enrolled at BMC in the fall of 1936 and graduated in the spring of 1941. She was one of only sixty students to hold degrees from BMC.

In the spring of 1937, Yamins met Louis Adamic during one of his visits to BMC. John Andrew Rice, founder and rector of the college, understood Adamic's influence on Yamins' path and ensured that she ate dinner with Adamic.