Oropharyngeal cancer : a fact sheet

Oropharyngeal Cancer A Fact Sheet from the North Carolina Central Cancer Registry, State Center for Health Statistics An HPV-associated cancer is a specific cellular type of cancer that is diagnosed in a part of the body where HPV (Human Papilloma Virus) is often found. These parts of the body include the cervix, vagina, vulva, penis, anus, rectum, and oropharynx (back of the throat, including the base of the tongue and tonsils). According to the CDC, each year there are about 34,800 new cancer cases caused by HPV in the United States. HPV can infect the mouth and throat and cause cancers of the oropharynx (back of the throat, including the base of the tongue and tonsils). This is called oropharyngeal cancer. HPV is thought to cause 70% of oropharyngeal cancers in the United States. It estimated that 93 people (72 males and 21 females) in North Carolina will be diagnosed with Oropharyngeal cancer and 43 people (33 males and 10 females) will die of Oropharyngeal cancer in 2020. Figure 1. 2013-2017 Percent of Oropharyngeal Cancer Cases by Age Group 85+ ™ 20-44 Percentages may not add up to 100 percent due to rounding. Incidence The percentage of cases of Oropharyngeal cancer from 2013 to 2017 is displayed by age group in Figure 1. About 4.7 percent of Oropharyngeal cancer cases were diagnosed in people younger than 45. October 2020 From 2013 to 2017, the age-adjusted incidence rate for Oropharyngeal cancer in North Carolina was 0.7 per 100,000 people per year. Non-Hispanic Black males have the highest incidence rate for Oropharyngeal cancer (Figure 2). From 2003 to 2017, Oropharyngeal cancer incidence rates have been stable for both men and women (Figure 3). Figure 2. 2013-2017 Oropharyngeal Cancer Incidence Rates by Race, Ethnicity and Gender 1.6 1.5 All Races and Non-Hispanic Non-Hispanic Hispanics Ethnicities Whites Blacks Race and Ethnicity ■ Males ■ Females 1.4 I 1.2 3 S. to 0 CL o 0.8 i« £. 0.4 * 0.2 a. 0.0 / Figure 3. 2003-2017 Oropharyngeal Cancer Incidence Trends by Gender . . & 4-P $ ^ •#'' ■#V ^ ^ # A & c§b У NN о # •£> ■£> -£> У «—Male —«—Female NC DEPARTMENT OF HEALTH AND HUMAN SERVICES Division of Public Health State of North Carolina ♦ www.nc.gov ♦ Department of Health and Human Services www.ncdhhs.gov ♦ North Carolina Division of Public Health ♦ www.publichealth.nc.gov State Center for Health Statistics ♦ www.schs.state.nc.us North Carolina DHHS is an equal opportunity employer and provider. Stage at Diagnosis* Figure 4 shows the stage distribution of Oropharyngeal cancer cases diagnosed from 2013 to 201 7. Approximately 73.9 percent of Oropharyngeal cancer cases were diagnosed at the localized or regional stage. Figure 4. 2013-2017 Percent of Oropharyngeal Cancer Cases by Stage Unknown Percentages may not add up to 100 percent due to rounding. Mortality From 2013 to 2017, the percentage of Oropharyngeal cancer deaths is displayed by age group in Figure 5. About 48.9 percent of deaths occurred in people ages 65 to 84. Figure 5. 2013-2017 Percent of Oropharyngeal Cancer Deaths by Age Group 20-44 Percentages may net add up to 100 percent due to rounding. The age-adjusted mortality rate of Oropharyngeal cancer from 2013 to 2017 was 0.3 per 100,000 people per year. When comparing Oropharyngeal cancer rates by race and ethnicity, non-Hispanic Black males have the highest mortality rate (Figure 6). Figure 6. 2013-2017 Oropharyngeal Cancer Mortality Rates by Race, Ethnicity and Gender 0.8 £ All Races and Non-Hispanic Non-Hispanic Hispanics Ethnicities Whites Blacks ■ Males ■ Females From 2003 to 2017, Oropharyngeal cancer mortality rates have been stable for both men and women (Figure 7). Figure 7. 2003-2017 Oropharyngeal Cancer Mortality Trends by Gender U.O c ■S 0 8 3 n / \/\/ . CL О U.O o' о r no . Ш - щ - Ш 8 О П 1 . У 4 . . 15 °-1 o: n <f& # # # # # <£> У # ■£> <P <3> cF & $ <§> c? У -F —♦—Male -e-Female Data Sources and Methods Data on North Carolina cases were obtained from the North Carolina Central Cancer Registry (CCR). Hospitals are the primary source of data. The CCR supplements hospital data with reports from physicians who diagnose cases in a non-hospital setting. The CCR also collects data from pathology laboratories and freestanding treatment centers. Data on cancer deaths were obtained from Statistical Services in the State Center for Health Statistics. Population data from the National Center for Health Statistics were used in the denominators of the rates, which are expressed per 100,000 people. Rates were age-adjusted using the 2000 United States Census data. To examine trends, three- year overlapping rates were used to improve stability over time. Stage at diagnosis was defined according to Surveillance, Epidemiology, and End Results Summary Stage guidelines as in situ, localized, regional, distant, and unknown/NA. For further information about the North Carolina CCR, visit www.schs.state.nc.us/units/ccr/. * According to the National Cancer Institute (NCI), “many cancer registries, such as NCI’s Surveillance, Epidemiology, and End Results Program (SEER), use summary staging. This system is used for all types of cancer. It groups cancer cases into five main categories: In situ Abnormal cells arc present only in the layer of cells in which they developed. Localized -Cancer is limited to the organ in which it began, without evidence of spread. Regional Cancer has spread beyond the primary site to nearby lymph nodes or organs and tissues. Distant — Cancer has spread from die primary site to distant organs or distant lymph nodes. Unknown —There is not enough information to determine die stage." Additional information on staging can be found at https://www.canccr.gov/about-canccr/diagnosis-staging/staging.