North Carolina Biotechnology Center...
...Creating Biotech Jobs
We make connections in these four areas to commercialize life-science ideas
and create jobs for North Carolina:
Biotech Growth Companies...
Economic Development...
Did You Know?
Research & Innovation...
...are where it all starts, so the Biotech Center helps to
move great life-science ideas into the marketplace. For
example:
Grant Helps Turn Tall Grass to Long Green
The pathway to life-science success in North Carolina
can take many twists and turns, like the work of
Thomas Ranney, Ph.D., a professor of horticultural
science at North Carolina State University’s Mountain
Horticultural Crops Research and Extension Center,
near Asheville.
Ranney received a Collaborative Funding Grant from
the Biotech Center in 2006 to commercialize a sterile
or seedless line of the popular ornamental landscape-
grass Miscanthus - an Asian plant that some fear could
otherwise become an invasive pest, like kudzu.
The $90,000 grant, supported through a Biotech Center
partnership with NCSU’s Kenan Institute, required a
commercial partner — in this case, the Research Triangle-
area’s Hoffman Nursery.
It’s producing results. Hoffman has a target to grow and
sell its unique, non-invasive Miscanthus in 2012. Ranney
is also developing a version for biofuels.
That grant is translating into new jobs for North
Carolinians — and new products for people everywhere.
neb iotech.
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Rebecca Howell (L), Joanna Cooper, Ben Bahr, Ph.D.
Workforce & Education...
... arc fundamental to growing North Carolina’s
knowledge economy. Here’s one of the many ways the
Biotech Center boosts N.C. students — from middle
schoolers to university postdocs:
Fellowships Propel Research Futures
It’s the old Catch-22 — you need experience to get a job,
but you can’t get experience without a job.
Young scientists can build that experience through the
Biotech Center’s Undergraduate Research Fellowships —
$5,000 awards to support research experiences for science
and engineering majors. These awards each summer give-
university students an opportunity to try bench science,
and their academic or company mentors gain new ideas.
Joanna Cooper, a University of North Carolina at
Pembroke student, earned one of the fellowships in 2010.
She studied with internationally respected molecular
biologist Ben Bahr, Ph.D. Her project explored the
underlying cause of a group of inherited metabolic diseases
The next year, Rebecca Howell, who left the real estate
industry to become a UNCP student, won the award, and
is also studying in Bahr’s lab.
Prof. Bahr is himself a Biotech Center success story; he’s
one of the 50-plus world-class experts we helped recruit
to North Carolina universities. Bahr’s commitment to
mentoring young scientists is another manifestation of our
programs’ impact on the statewide biotech community.
ncbiotech. org/training
...require funding to survive their lean early years. One-
source of support for these major job engines is a Biotech
Center loan:
Piedmont Pharma Spins Loan into Partnerships
A decade ago Piedmont Pharmaceuticals started on a
path to commercialize a product that kills head lice.
Now, while the Greensboro firm is working toward U.S.
Food and Drug Administration approval, it is licensing its
unique, patented parasite-killing system to companies that
are selling it around the world. Its R&D has also made it
a hit with big-name animal- health collaborators, including
Pfizer and Bayer.
Piedmont’s path to success included a well-timed $150,000
Small Business Research Loan from the Biotech Center.
... reaps an immediate reward in jobs for North Carolina.
The Biotech Center’s life-science expertise is a critical
contribution to recruitment projects, including:
N.C/s Tobacco Legacy Turns Over a New Leaf
Time was, a new tobacco company in North Carolina
wouldn’t be international news.
We’ve turned over a new leaf with Medicago’s new
$42 million facility in Research Triangle Park.
It’s designed to produce new vaccines quickly using
tobacco plants grown in greenhouses.
Recruitment specialists from the Biotech Center worked
with partner organizations to show the Canadian
company why North Carolina would be the right home
for its new facility.
Medicago execs liked what they saw.
Already a world leader in vaccine research and
manufacturing, North Carolina is a business-friendly
state with a highly trained workforce and an unparalleled
quality of life. We’re home to the nation’s third-largest
life-science sector — some 530-plus companies employing
about 60,000 people. That includes the biggest names in
pharmaceuticals and agriculture.
North Carolina. International news in the life sciences.
ncbiotech. org/W hyNC
Eric Barnett, M.D., executive vice president of business
development, says Piedmont is excited to be entering
a critical growth phase. But he says it might not have
survived its start-up years without that early loan.
“It’s sometimes not so much the dollar amount of these
Biotech Center loans that makes them so important. It’s their
timing. They buy a young company time to get to the next
level. And the vetting involved helps recipients demonstrate
their investment worthiness to others. ”
— Eric Barnett, M.D., Executive Vice President of Business Development,
Piedmont Pharmaceuticals
ncbiotech.org/growth
• Willow bark, yarrow, wild ginger — North Carolina's
mountain west is home to these and 2,500 species of plants,
many with potential medical uses. Bent Creek Institute
in Asheville, established with help from the Biotech Center,
includes the first North American germplasm repository to
help protect and study precious regional flora.
• In 2003, the
Pillowtex textile mill
near Charlotte went
bankrupt, displacing
all 7,650 workers —
the largest mass
layoff in industry
history. Today, that
6-million-square-
foot, old-economy
site is being reused in the $1.5 billion North Carolina
Research Campus, where scientists study foods, nutrition
and health.
• It once was science fiction. Now, scientists in North Carolina
can take a few cells from a human body and coax them to
become new organs and tissues. Regenerative medicine
is making North Carolina a "body-building" capital, thanks
to scientists like Anthony Atala, M.D., at Wake Forest
University. Children are already thriving with new bladders
made this way, and more breakthroughs are near.
• Spider silk is five times stronger than steel, 10 times more
elastic than Kevlar. But spiders can't be trained to produce
it in useable ways. Scientists at Charlotte biotech company
EntoGenetics put spider genes in silkworms to spin spider
silk — a bulletproof combination with huge potential.
• Pizza-topping button mushrooms. Farm-pond duckweed.
Tobacco leaves. They're all being used in North Carolina
as living factories, producing vaccines and other medicines
faster and more efficiently than ever before.